pentobarbital will decrease the extent or effect of nitrendipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Not known.pentobarbital will lessen the level or impact of tipranavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.pentobarbital and daridorexant both boost sedation. Mo